Melting Point Certified Reference Materials for Organic Substances: Development Perspectives

The field of the melting point measurements high-purity organic substances today includes a large number measuring instruments used in medicine, biology, and production perfumery cosmetic products. purpose research is to identify features justify approaches development certified reference materials provided with metrological traceability SI base measurement units «temperature» (°C). objectives included justification choice substances-candidates for CRMs; determination certification procedure RMs; establishment restrictions affecting procedure; estimation uncertainty values CRMs. In course research, state analysis assurance was performed. An overview complex designed measure purity range from +40 °C +250 presented, its functional diagram given. basic requirements substancescandidates CRMs are identified. study presents results determining benzophenone, benzoic acid, succinic anthracene, caffeine obtained by direct phase transition temperature indirect based on recording moment optical transparency under study. interlaboratory comparisons samples studied which made it possible obtain reliable data emergence at different heating rates. A method reconciling proposed; consists presenting value determined thermodynamic mode, as well various rates additional characteristics substance passports developed Research further work formulated. theoretical significance lies methodological pure substances, make improve accuracy thermal higher quality level.